Age? 28 now (24 when this started) -Which 19-nor substance gave you PDD (Deca, Tren, NPP etc.)? Cycle length? Dosage? Tren 8 week cycle I took the following : Test E and Tren A at 2ml a week (1 mill every 4 days) for 8 weeks. That makes it: 600mg Test E a week 200mg Tren A a week -Date your PDD - started summer of 2018 not sure exact date -Has it been at least 6 months since you last administered the said 19-nor and have your Testosterone, Free Test and Estrogen levels returned to normal either naturally or through TRT? (If the answer to either of these is no then we should be cautious to assume that you actually have PDD. Your focus should be optimising your Test levels) -Are you now on TRT or have your Test/ Free Test/ Estro levels returned to normal naturally? Not on TrT -Give a rating for the following out of 10 compared with before PDD. 10/10 means the same as before (feel free to give further comments): -Sex drive 5/10 used to be lower -Erection quality 6/10 again used to be lower -Orgasm Quality 3/10 -Ability to experience negative emotion - easily , not sure how to rate this -Ability to experience positive emotion - never as happy as I used to be emotionally numb compared -Ability to experience feelings of confidence (feeling good about being you) okay -Feelings of pleasure seeking - again numb -Feelings of hunger (thinking about what you will eat and salivating) not noticed this personally -Ability to handle stress/ not be affected by stress - stressed very easy although again this has slowly improved with time and supplements -Memory and cognitive ability - 6/10 my memory used to be really good never stumbled on words and names and not not so great -Sleep quality 5/10 -Energy levels 6/10 -Depression - It went sky high but I’ve calmed it down -Anxiety - up and down but way above what it was pre Tren. Again something I’ve worked so hard on -Have you seen any change (improvement or worsening) of symptoms since PDD started? Do you know what brought about these changes? -Any other symptoms of PDD or changes you think were caused by PDD? -Any other comments? I’ll share a big post on what I know. I’ve done so much research on this topic , including hours and hours and hours in research papers and developing understanding of medical reviews

So without dragging this on and boring everyone too much after 4 years of suffering I’ve looked into so many avenues , drs and remedies. Within my first year I probably was very similar to many of you reading this where I thought my issue was due to a testosterone issue, and for some I’m sure it is. Following this I went down the rabbit hole of prolactin , again after Tren decca etc it’s not unusual to see increased prolactin and again this could be the issue for some of you. So the blood tests I recommended for a good starting point: Total test Free test FSH LH SHBG E2 DHEA Androstenedione TSH FT3 FT4 Prolactin Cortisol Progesterone The systems at work are so complex and interact in many different processes, as a result it’s hard to understand what starting a negative feedback loop or what is an impact of a negative feedback loop. So what did I start taking first to fix my issue and how well did it work. (The boost testosterone stage) Clomid and tamoxifen - 2/10 ramped up my test but almost little to no effect on libido / Tren dick (The fix the reward system stage I.e. dopamine) Uridine monophosphate (trying to up-regulate d2 receptors) Sam - E ( helps produce brain chemicals e.g dopamine serotonin) Choline CDP ( increase d2 receptor dentistry) - 5/10 had good improvements in this stage less so with the Tren dick but more with my general mental health which had unfortunately taken a battering due to the issue. Be warned I rushed into taking these supplements which are powerful, they caused me many light headed dizzy spells after a while and also muscle twitches which made me concerned I had MS Next well being supplement stage: Vitamin E 400iu P5P 200mg Glucosamine (G), calcium (Ca) & Chondroitin (Ch) (stared this week). G 384mg Ca. 100mg Ch. 36mg Methyl folate. 400ug Omega 3. 1200mg providing 720mg omega 3 fatty acid of which 240mg DHA and 360mg EPA ZMA - zinc 10mg Magnesium 150mg & vit b6 3.5mg Issue is it’s hard to know what was working and wasn’t. 5/10 it boosts overall health and libido would come in waves but it wasn’t tailored to me it was just me guessing and researching. Next probiotics 6/10 massive improvements on health and well being. Please note most probiotics are duds, by this I mean they just don’t offer what they say they do. Better to spend a little more here. Hcg - 6/10 improvements HCG doesn’t just increase LH and therefore testosterone it had effects on the brain and has been heavily researched by those in the post finastride syndrome community who we share many symptoms from. Cialis - 6/10 it won’t improve libido as such. Well not from a chemical stand point but it will help you maintain a better erection and this psychologically helped me want sex. This also ensure my penis received blood supply especially during nocturnal erections helping to maintain its function until this is fixed Next was tailored naturopathic drugs. (I’ll edit this when home to add it in) Things I’ve investigated and the hormones associated thyroid, adrenal , pituarity, testicles. Brain - dopamine, serotonin Gut microbe Nerves. Post finasteride syndrome Sleep hygiene Even sexual health. Please also do you’re own research I can offer advice on any of these subjects above but it’s exactly that just advice so please also seek medical experts in the area. I’m happy to really deep dive into the supplements I took above. Overall in last 4 years I’ve had some good gains in my health and general well being. I’ve gone from suicidal to much more positive I still have my down days but not as many. Drs who are often consulted in this area : Dr o Connor Dr Mariano Dr Chrysler Dr Robert Stevens (UK based - brilliant YouTube channel) Dr Paula Rochelle

@"leeds24"#p16 Nice so you saw some good improvements in mood by up regulating d2 receptors. I've had some Uridine for a while but never tried it. I'd be interested to know more about what your thyroid and adrenal tests said and what you did for them. I remember from T-nation that you had high cortisol? By the way, do you mind if I merge this post with your other one? That way we can keep your case in one place instead of talking in both posts.

@"james993"#p21 So I’m not sure how to edit the above post but here are the supplements I have been taking under Dr Rochelle 1. Clematis Combination Drops 2. Hypothaltem 3. Avipaxin 4. Ashwagandha 5. HPS (axis) Lf 6. Clucogen complex

4 year sufferer - my journey

leeds24

Happy for you to merge the posts I’ll catch it up with the detail either later today or tomorrow (work is full on at the min)

james993

leeds24 Lol no rush, we've had this for years, I'm sure I can wait.

That's encouraging to hear that you've improved sex drive a bit, I'd kill for 5/10 sex drive.

Also sounds like focusing on sleep could benefit you, especially since you report stress problems. I've learned a bit about sleep so can give advice.

leeds24

james993 So I’m not sure how to edit the above post but here are the supplements I have been taking under Dr Rochelle

Clematis Combination Drops
Hypothaltem
Avipaxin
Ashwagandha
HPS (axis) Lf
Clucogen complex

james993

Hey bro, you asked me before what other tests I have done. Just made a new blog with some of the tests.

james993

leeds24 So whats your plan now? Also, will you be retesting your adrenals at some point to make sure you're going in the right direction?

james993

When you did your tren cycle, did you experience any digestive issues? Bloating, constipation, diarrhea? Or after cycle etc?

Alfo1990

james993 hi I’m alfo from italy and I take deca last time 1 year ago and I have bog problems nobody in Italy understand what I have I lose sensation in my dick also in my nipples my cum is very weird is like solid and even with cialis I have problem

james993

Alfo1990 Hi Alfo, sorry to hear that. Would you mind making a post to introduce yourself?

Read this post and use the "introduce yourself" template:

https://www.permanentdecadick.com/d/4-new-users-please-read

Thanks

Alfo1990

I can t open this post you send me I try but not work

james993

Alfo1990 Even if you click the title "New Users Please Read" ?